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Semaglutide: Works primarily through the GLP-1 receptor, enhancing insulin secretion when glucose levels are high and reducing appetite by acting on brain receptors related to hunger and satiety
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Side effects by dose A meta-analysis of 10 trials (6,836 participants) found total GI event rates of 39% at 5 mg, 46% at 10 mg, and 49% at 15 mg
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